[HTML][HTML] Effects of obesity on bone metabolism

JJ Cao - Journal of orthopaedic surgery and research, 2011 - Springer
Obesity is traditionally viewed to be beneficial to bone health because of well-established
positive effect of mechanical loading conferred by body weight on bone formation, despite …

Effects of high‐protein diets on fat‐free mass and muscle protein synthesis following weight loss: a randomized controlled trial

SM Pasiakos, JJ Cao, LM Margolis… - The FASEB …, 2013 - Wiley Online Library
The purpose of this work was to determine the effects of varying levels of dietary protein on
body composition and muscle protein synthesis during energy deficit (ED). A randomized …

High-fat diet decreases cancellous bone mass but has no effect on cortical bone mass in the tibia in mice

JJ Cao, BR Gregoire, H Gao - Bone, 2009 - Elsevier
Body mass has a positive effect on bone health. Whether mass derived from an obesity
condition or excessive fat accumulation is beneficial to bone has not been established; neither …

Expression of RANKL and OPG correlates with age‐related bone loss in male C57BL/6 mice

J Cao, L Venton, T Sakata… - Journal of Bone and …, 2003 - academic.oup.com
Osteoblasts regulate the recruitment and activity of osteoclasts through expression of RANKL
and osteoprotegerin (OPG). To determine whether expression of RANKL and OPG change …

A global view of the selectivity of zinc deprivation and excess on genes expressed in human THP-1 mononuclear cells

…, MP Popp, L Liu, J Cao… - Proceedings of the …, 2003 - National Acad Sciences
Among the micronutrients required by humans, zinc has particularly divergent modes of
action. cDNA microarray and quantitative PCR technologies were used to investigate the zinc …

Green tea and bone metabolism

CL Shen, JK Yeh, JJ Cao, JS Wang - Nutrition research, 2009 - Elsevier
Osteoporosis is a major health problem in both elderly women and men. Epidemiological
evidence has shown an association between tea consumption and the prevention of age-…

Aging increases stromal/osteoblastic cell‐induced osteoclastogenesis and alters the osteoclast precursor pool in the mouse

JJ Cao, TJ Wronski, U Iwaniec, L Phleger… - Journal of Bone and …, 2005 - academic.oup.com
Stromal/osteoblastic cell expression of RANKL and M‐CSF regulates osteoclastogenesis.
We show that aging is accompanied by increased RANKL and M‐CSF expression, increased …

Diet‐induced obesity alters bone remodeling leading to decreased femoral trabecular bone mass in mice

JJ Cao, L Sun, H Gao - Annals of the New York Academy of …, 2010 - Wiley Online Library
Obesity‐derived body mass may be detrimental to bone health through not well‐defined
mechanisms. In this study we determined changes in bone structure and serum cytokines …

[HTML][HTML] Selenium in bone health: roles in antioxidant protection and cell proliferation

H Zeng, JJ Cao, GF Combs Jr - Nutrients, 2013 - mdpi.com
Selenium (Se) is an essential trace element for humans and animals, and several findings
suggest that dietary Se intake may be necessary for bone health. Such findings may relate to …

Blocking antibody to the β-subunit of FSH prevents bone loss by inhibiting bone resorption and stimulating bone synthesis

LL Zhu, H Blair, J Cao, T Yuen, R Latif… - Proceedings of the …, 2012 - National Acad Sciences
Low estrogen levels undoubtedly underlie menopausal bone thinning. However, rapid and
profuse bone loss begins 3 y before the last menstrual period, when serum estrogen is …