This is the first prospective study of the effects of human gut microbiota and metabolites on
immune checkpoint inhibitor (ICT) response in metastatic melanoma patients. Whereas many …

Inflammatory diseases of the gastrointestinal tract are frequently associated with dysbiosis 1
, 2 , 3 , 4 , 5 , 6 , 7 , 8 , characterized by changes in gut microbial communities that include …

Candida albicans colonization is required for invasive disease 1 , 2 , 3 . Unlike humans,
adult mice with mature intact gut microbiota are resistant to C. albicans gastrointestinal (GI) …

Candida albicans fungemia in cancer patients is thought to develop from initial gastrointestinal
(GI) colonization with subsequent translocation into the bloodstream after administration …

Many of the virulence factors produced by the opportunistic human pathogen Pseudomonas
aeruginosa are quorum‐sensing (QS) regulated. Among these are rhamnolipids, which …

Pseudomonas aeruginosa is a leading cause of pneumonia, and many components of the
innate immune system have been proposed to exert important effects in preventing lung …

α-Fetoprotein (AFP) is often derepressed in human hepatocellular carcinoma. Peptide
fragments of AFP presented in the context of major histocompatibility molecules could serve as …

The collection of microbes that live in and on the human body – the human microbiome –
can impact on cancer initiation, progression, and response to therapy, including cancer …

Aire induces ectopic expression of peripheral tissue antigens (PTAs) in thymic medullary
epithelial cells, which promotes immunological tolerance. Beginning with a broad screen of …

α fetoprotein (AFP)-derived peptide epitopes can be recognized by human T cells in the
context of MHC class I. We determined the identity of AFP-derived peptides, presented in the …