Primary squamous cell carcinoma of the breast in association with Zuska's disease

Breast Cancer. 2018 May;25(3):365-369. doi: 10.1007/s12282-017-0819-3. Epub 2017 Nov 17.

Abstract

Breast cancer is the most common malignancy in women in the UK with well-defined algorithms of management in place in the western world. Squamous cell carcinoma of the breast is a rare entity and as such knowledge about the pathophysiology, treatment and prognosis are still uncertain. The report describes an unusual case of squamous cell carcinoma arising in an area of Zuska's disease of the breast. It illustrates the heterogeneity of the imaging findings with review of the literature. Decisions on management should be taken on an individual basis with full discussion in the multidisciplinary team meetings where all facets of the case are considered.

Keywords: Breast cancer; Imaging; Squamous cell carcinoma of the breast; Zuska’s disease.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Abscess / complications*
  • Abscess / diagnostic imaging
  • Abscess / pathology
  • Abscess / surgery
  • Aged, 80 and over
  • Breast / diagnostic imaging
  • Breast / pathology
  • Breast / surgery
  • Breast Diseases / complications*
  • Breast Diseases / diagnostic imaging
  • Breast Diseases / pathology
  • Breast Diseases / surgery
  • Breast Neoplasms / diagnostic imaging
  • Breast Neoplasms / etiology*
  • Breast Neoplasms / pathology
  • Breast Neoplasms / surgery
  • Carcinoma, Squamous Cell / diagnostic imaging
  • Carcinoma, Squamous Cell / etiology*
  • Carcinoma, Squamous Cell / pathology
  • Carcinoma, Squamous Cell / surgery
  • Female
  • Fistula / complications*
  • Fistula / diagnostic imaging
  • Fistula / pathology
  • Fistula / surgery
  • Humans
  • Image-Guided Biopsy
  • Mammography
  • Mastectomy
  • Prognosis
  • Sentinel Lymph Node Biopsy
  • Ultrasonography, Mammary

Supplementary concepts

  • Zuska's Disease